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High-potassium foods Pleurisy root Potassium supplements | |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
| Interactions common to many, if not all, Beta-Adrenergic Blockers are described in this article. Interactions reported for only one or several drugs in this class may not be listed in this article. Some drugs listed in this article are linked to articles specific to that respective drug; please refer to those individual drug articles. The information in this article may not necessarily apply to drugs in this class for which no separate article exists. If you are taking a Beta-Adrenergic Blocker for which no separate article exists, talk with your doctor or pharmacist. | |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Potassium
Some beta-adrenergic blockers (called “nonselective” beta blockers) decrease the
uptake of potassium from the blood into the cells,1 leading to excess potassium in
the blood, a potentially dangerous condition known as hyperkalemia.2 People taking
beta-blockers should therefore avoid taking potassium supplements, or eating large quantities
of fruit (e.g.,
bananas), unless directed to do so by their doctor.
Pleurisy root
As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides,
it is best to avoid use of pleurisy root with heart medications such as
beta-blockers.3
1. Rosa RM, Silva P, Young JB, et al. Adrenergic modulation of extrarenal potassium disposal. N Engl J Med 1980;302:431–4.
2. Lundborg P. The effect of adrenergic blockade on potassium concentrations in different conditions. Acta Med Scand Suppl 1983;672:121–6 [review].
3. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: Pharmaceutical Press, 1996, 213–4.
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