|
|
Potassium | |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
| Adverse interaction |
None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Potassium and other
nutrients
Prolonged and frequent use of stimulant laxatives, including bisacodyl, may cause excessive
and unwanted loss of water, potassium, and other nutrients from the body.1
2 Bisacodyl should be used for a maximum of one week, or as directed on the package
label. Excessive use of any laxative can cause depletion of many nutrients. In order to
protect against multiple nutrient deficiencies, it is important to not overuse
laxatives.3 People with constipation should consult with their doctor or pharmacist
before using bisacodyl.
Food
Bisacodyl tablets are enteric coated to pass through the stomach and dissolve in the small
intestine. Milk, dairy products, vegetables, almonds, chestnuts, and other foods can cause the
enteric coating to dissolve in the stomach, leading to irritation and cramping.4
People should take bisacodyl one hour before or two hours after meals to avoid this
problem.
1. Fleming BJ, Genuth SM, Gould AB, Kaminokowski MD. Laxative induced hypokalemia, sodium depletion, and hyperreninemia. Effects of potassium and sodium replacement on the rennin angiotensin system. Ann Intern Med 1975;83:60–2.
2. Threlkeld DS, ed. Gastrointestinal Drugs, Laxatives. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1991, 319a.
3. Threlkeld DS, ed. Gastrointestinal Drugs, Laxatives. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1991, 319a.
4. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 49.
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