|
|
Henbane* | |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Henbane (Hyoscyamus niger)
Antihistamines, including brompheniramine, can cause “anticholinergic” side
effects such as dryness of mouth and heart palpitations. Henbane also has anticholinergic
activity and side effects. Therefore, use with brompheniramine could increase the risk of
anticholinergic side effects,1 though apparently no interactions have yet been
reported with brompheniramine and henbane. Henbane should not be taken except by prescription
from a physician trained in its use, as it is extremely toxic.
Alcohol
Brompheniramine causes drowsiness.2 Alcohol may intensify this effect and increase
the risk of accidental injury.3 To prevent problems, people taking brompheniramine
or brompheniramine-containing products should avoid alcohol.
1. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 146.
2. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 192a.
3. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO, Facts and Comparisons, May 1998, 192a.
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