|
|
Henbane* | |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Henbane (Hyoscyamus niger)
Antihistamines, including clemastine, can cause “anticholinergic” side effects
such as dryness of mouth and heart palpitations. Henbane also has anticholinergic activity and
side effects. Therefore, use with clemastine could increase the risk of anticholinergic side
effects,1 though apparently no interactions have yet been reported with clemastine
and henbane. Henbane should not be taken except by prescription from a physician trained in
its use, as it is extremely toxic.
Alcohol
Clemastine causes drowsiness.2 Alcohol may intensify this effect and increase the
risk of accidental injury.3 To prevent problems, people taking clemastine or
clemastine-containing products should avoid alcohol.
1. Blumenthal M, ed. The Complete German Commission E Monographs. Austin, TX: American Botanical Council, 1998, 146.
2. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 191c.
3. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 191c.
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