|
|
Henbane* | |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Henbane (Hyoscyamus niger)
Antihistamines, including dimenhydrinate, can cause “anticholinergic” side effects
such as dryness of mouth and heart palpitations. Henbane also has anticholinergic activity and
side effects. Therefore, use with dimenhydrinate could increase the risk of anticholinergic
side effects,1 though apparently no interactions have yet been reported with
dimenhydrinate and henbane. Henbane should not be taken except by prescription from a
physician trained in its use, as it is extremely toxic.
Alcohol
Dimenhydrinate causes drowsiness.2 Alcohol may intensify this effect and increase
the risk of accidental injury.3 To prevent problems, people taking dimenhydrinate
or dimenhydrinate-containing products should avoid alcohol.
1. Blumenthal M, ed. The Complete German Commission E Monographs. Austin, TX: American Botanical Council, 1998, 146.
2. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1989, 188–94c.
3. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1989, 188–94c.
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