Shop products for Methylphenidate 
Also indexed as: Metadate® ER, Methylin®, PMS-Methylphenidate®, Riphenidate®, Ritalin®, Ritalin® -SR
Methylphenidate is a stimulant drug with actions similar to amphetamines. It is used as an adjunct to a complete programme to treat children with attention deficit-hyperactivity disorder. Methylphenidate is also used to treat people with narcolepsy.
Summary of
Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem
contradictory. For clarification, read the full article for details about the summarized
interactions.
 Avoid: Adverse interaction—Avoid these supplements
when taking this medication because taking them together may cause undesirable or dangerous
results. |
Alcohol |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Interactions with Foods and Other Compounds
Food
Some researchers have recommended that methylphenidate be taken 30 to 45 minutes before
meals,1 although it has been reported that methylphenidate was absorbed
faster2 and was equally effective3 taken with food. Sustained-release
methylphenidate (Ritalin®-SR) tablets should be swallowed whole, without crushing or
chewing.4
Alcohol
Methylphenidate may impair physical coordination and cause dizziness or
drowsiness.5 Alcohol may intensify these effects, increasing the risk of accidental
injury. To prevent problems, people taking methylphenidate should avoid alcohol.
References
1. Threlkeld DS, ed. Central Nervous System Drugs, Miscellaneous Psychotherapeutic Agents, Methylphenidate HCl. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1997, 268t–8v.
2. Chan YP, Swanson JM, Soldin SS, et al. Methylphenidate hydrochloride given with or before breakfast: II. Effects on plasma concentration of methylphenidate and ritalinic acid. Pediatrics 1983;72:56–9.
3. Swanson JM, Sandman CA, Deutsch C, Baren M. Methylphenidate hydrochloride given with or before breakfast: I. Behavioral, cognitive, and electrophysiologic effects. Pediatrics 1983;72:49–55.
4. Threlkeld DS, ed. Central Nervous System Drugs, Miscellaneous Psychotherapeutic Agents, Methylphenidate HCl. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1997, 268t–8v.
5. Threlkeld DS, ed. Central Nervous System Drugs, Miscellaneous Psychotherapeutic Agents, Methylphenidate HCl. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1997, 268t–8v.
