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| Rating | Health Concerns |
|---|---|
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High cholesterol and high triglyceride levels |
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary
studies suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but
minimal or no scientific evidence. For a supplement, little scientific support and/or minimal
health benefit. | |
Historically, maitake has been used as a tonic and adaptogen (a substance that invigorates or strengthens the system). Along with other “medicinal” mushrooms, such as shiitake and reishi, maitake was used as a food to help promote wellness and vitality.
A common denominator among some mushrooms and some herbs is the presence of complex polysaccharides in their structure. These active constituents help support immune system function and are sometimes called immunomodulators. The polysaccharides present in maitake have a unique structure and are among the most powerful studied in test tubes to date.2 The primary polysaccharide, beta-D-glucan, is well absorbed when taken orally and is being studied as a potential tool for prevention and treatment of cancer and as a adjunctive treatment for HIV infection.3 4 Animal studies suggest maitake may lower serum cholesterol and triglycerides.5 6 However, this research is still preliminary and requires human trials for confirmation.
Maitake can be used as a food or tea and is also available as a capsule or tablet containing the entire fruiting body of the mushroom. For maitake, the fruit body is higher in polysaccharides than the mycelium, which is why it is recommended. Whole-mushroom maitake supplements, 3–7 grams per day, can be taken.7 Liquid maitake extracts with variable concentrations of polysaccharides are available, and should be taken as directed.
Used as recommended above, there have been no reports of side effects with maitake.
At the time of writing, there were no well-known drug interactions with maitake.
1. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 110–5.
2. Nanba H, Hamaguchi AM, Kuroda H. The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake). Chem Pharm Bull 1987;35:1162–8.
3. Yamada Y, Nanba H, Kuroda H. Antitumor effect of orally administered extracts from fruit body of Grifola frondosa (maitake). Chemotherapy 1990;38:790–6.
4. Nanba H. Immunostimulant activity in vivo and anti-HIV activity in vitro of 3 branched b-1–6-glucans extracted from maitake mushrooms (Grifola frondosa). VIII International Conference on AIDS, Amsterdam, 1992 [abstract].
5. Kubo K, Nanba H. Anti-hyperliposis effect of maitake fruit body (Grifola frondosa). I. Biol Pharm Bull 1997;20:781–5.
6. Adachi K, Nanba H, Otsuka M, Kuroda H. Blood pressure lowering activity present in the fruit body of Grifola frondosa (maitake). Chem Pharm Bull 1988;36:1000–6.
7. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 110–5.
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