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| Rating | Health Concerns |
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Benign prostatic hyperplasia (in combination with glycine and glutamic acid) |
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary
studies suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but
minimal or no scientific evidence. For a supplement, little scientific support and/or minimal
health benefit. | |
Since alanine is synthesised in the body and is also provided by most foods that are sources of protein, deficiencies are unlikely to occur.3
Most people do not need to supplement with alanine; for those who do use this amino acid as a supplement, appropriate amounts should be determined with the consultation of a physician.
Alanine is free of side effects for the vast majority of people who take it; however, people with kidney or liver disease should not consume high intakes of amino acids without consulting a healthcare professional.
At the time of writing, there were no well-known drug interactions with alanine.
1. Damrau F. Benign prostatic hypertrophy: Amino acid therapy for symptomatic relief. J Am Geriatrics Soc 1962;10(5):426-30.
2. Feinblatt HM, Gant JC. Palliative treatment of benign prostatic hypertrophy. Value of glycine-alanine-glutamic acid combination. J Maine Med Assoc 1958;March.
3. Zello GA, Wykes LF, Ball RO, et al. Recent advances in methods of assessing dietary amino acid requirements for adult humans. J Nutr 1995;125:2907–15.
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