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Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary
studies suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but
minimal or no scientific evidence. For a supplement, little scientific support and/or minimal
health benefit. | |
Although molybdenum is an essential mineral, no deficiencies have been reported in humans.
No recommended dietary allowance (RDA) has been established for molybdenum. The estimated range recommended by the Food and Nutrition Board as safe and adequate is 75–250 mcg per day for adults.
Molybdenum is needed to convert purine to uric acid, and excessive intake could, in rare cases, increase uric acid levels and potentially trigger gout. Molybdenum interferes with the absorption of copper; long-term supplementation with molybdenum could, in theory, result in copper deficiency. Molybdenum has been reported to cause psychosis in a patient taking 300 to 800 mcg per day for 18 days. This report is as yet unsubstantiated by any other human or animal research.2
At the time of writing, there were no well-known drug interactions with molybdenum.
1. Johnson JL, Wuebbens MM, Mandell R, et al. Molybdenum cofactor deficiency in a patient previously characterized as deficient in sulfite oxidase. Biochem Med Metabol Biol 1988;40:86–93.
2. Momcilovic B. A case report of acute human molybdenum toxicity from a dietary molybdenum supplement—a new member of the “Lucor metallicum” family. Arh Hig Rada Toksikol 1999;50:289–97.
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